Anti-inflammatory Effects of Copaxone on the Level of Adhesion Molecule Expression Patterns under Short- and Long-term Treatment

Introduction/Objectives: To analyse the infl uence of shortand long-term glatiramer acetate (GA) treatment on expression patterns of cell surfacebound adhesion molecules (AM) on peripheral blood mononuclear cells (PBMC) from patients with relapsing remitting multiple sclerosis (RRMS). BACKGROUND: GA is baseline therapy for the treatment of RRMS. It is known to reduce relapse frequencies and to delay disease progression but the exact mechanisms of action remain elusive. Here, we investigate AM expression levels on PBMC from MS patients under short-and long-term GA therapy and from healthy controls.